For details see Histiocytic lesions
Clinical features
- Lung involvement occurs in 23-50%
- Often associated to pneumothorax, and Pneumocystis Jirovecii pneumonia
- More frequent in the upper lobes
- Focal or diffuse
- Nodular solid or cystic lesions
Cytopathology
For details see Histiocytic lesions
The authors do not have any experience of fine needle aspiration in this particular presentation in children.
Immunocytochemistry
For details see Histiocytic lesions
Modern Techniques of Diagnosis
For details see Histiocytic lesions
Differential Diagnosis
- Inflammatory conditions associated to Langerhans cell hyperplasia
- Other Histiocytic conditions that might affect the lung (ex: sarcoidosis)
Main points
- 10-20% progress to respiratory failure