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Čeština
Metastatic tumors
- Colorectal carcinoma
- Tall (columnar), dark (hyperchromatic) cells and necrosis
- Breast carcinoma and gastric carcinoma
- Signet ring cells
- Prostate carcinoma
- Microacini
- Prominent nucleoli
- Immunoreactive for Prostatic Specific Antigen and Prostatic Acid Phosphatase
- Well-differentiated neuroendocrine tumors
- Eccentrically placed nuclei
- salt-and-pepper chromatin pattern
- Abundant granular cytoplasm
- Single cells, loosely cohesive clusters and rosettes
- Immunoreactive for neuroendocrine markers
- Small cell carcinoma
- Isolated and loosely cohesive cells
- Nuclear molding
- Hyperchromatic nuclei with finely granular chromatin and incospicuous nucleoli
- Round, polygonal or spindle cells
- Squamous cell carcinoma
- Small, dark nuclei
- Abundant cytoplasm with a hard, glassy appearance (orange with Papanicolaou stain and gray with Romanowsky-type stain) in well-differentiated tumors
- Sarcoma
- Spindle cells (differential diagnosis: metastatic sarcomatoid carcinoma)
- Malignant melanoma
- Abundant, sometimes pigmented, cytoplasm
- Intranuclear pseudoinclusions and macronucleoli
- Single cell pattern
- Finely granular melanin pigment
- Immunoreactive for S-100 and HMB-45
- Lymphoma