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It is the most common benign tumor of the liver. It is composed of dilated vascular spaces lined by endothelial cells. When a spindle cell lesion is observed on FNA, it is most likely a hemangioma. In some cases only blood or benign hepatocytes are observed.

Cytologic diagnostic features

  • Blood
  • Hepatocytes
  • Three-dimensional arcades of bland elongated spindle cells
  • Compact, dense coils of spindle cells
  • Rare isolated spindle cells
  • Vascular channels lined by endothelial cells (cell block sections)