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Las características biológicas y morfológicas del carcinoma invasivo de células escamosas

Histological section of keratinising squamous carcinoma. Note keratin whorls and chords of tumour tissue invading the stroma.
Histological section of non keratinising squamous carcinoma. There are some chords of tumour tissue invading the stroma which also contains inflammatory cells and discrete bizare tumour cells with abnormal nuclei and abundant cytoplasm.

 

El diagnóstico citológico del carcinoma invasivo de células escamosas

Well differentiated invasive squamous carcinoma. Note small squamous cells with pyknotic nuclei which vary in size and shape. Cytoplasm is highly keratinised a small cluster of undifferentiated tumour cells are also seen in the right hand corner. Note tumour diathesis.
Non keratinising invasive squamous carcinoma. Note small squamous cells with pyknotic nuclei which vary in size and shape. Cytoplasm is not keratinised. Note tumour diathesis.
Highly keratinised squames in an invasive squamous carcinoma.
Non keratinising squamous carcinoma. Some individual cells with non keratinised cytoplasm and irregular nuclei can be seen. A group of undifferetiated tumour cells is in the foreground. Note tumour diathesis.
A dense three dimensional cluster of undifferentiated tumour cells in a smear from an invasive carcinoma. The hyperchromatic nuclei overlap and mould each other. The abnormal nucleus structure becomes apparent at higher magnification and the squamous nature of the lesion can be ascertained by examining the edge of the cluster where the cytoplasmic structure can be seen.
A dense three dimensional cluster of undifferentiated tumour cells in a smear from an invasive carcinoma. The hyperchromatic nuclei overlap and mould each other. The abnormal nucleus structure becomes apparent at higher magnification and the squamous nature of the lesion can be ascertained by examining the edge of the cluster where the cytoplasmic structure can be seen.
A dense three dimensional cluster of undifferentiated tumour cells in a smear from an invasive carcinoma. The hyperchromatic nuclei overlap and mould each other. The abnormal nucleus structure becomes apparent at higher magnification and the squamous nature of the lesion can be ascertained by examining the edge of the cluster where the cytoplasmic structure can be seen.