EPITHELIOID LESIONS
Schwannoma
Clinical features Fig 34 – Schwannoma –Cohesive tissue fragments. Fragments of uniform spindle shaped cells in a moderate collagenous matrix (H&E) Immunocytochemistry Differential Diagnosis
Malignant peripheral nerve sheet tumour
Clinical features Fig 33a – Malignant peripheral nerve sheath tumor –Cohesive tissue fragment showing an epithelioid-like pattern area (H&E) Immunocytochemistry Electron microscopy Genetic studies Differential Diagnosis Main points
Neurofibroma
Clinical features Cytopathology Immunocytochemistry Differential Diagnosis Main points
Synovial sarcoma
For more details see biphasic tumour
Fibrosarcoma of infancy
Clinical features Cytopathology Genetic studies Differential Diagnosis Main points Treatment: complete excision
Fibromatosis colli
Clinical features Fig 31a – Fibromatosis colli – Single fibroblasts, and regenerating multinucleated muscle fibres (H&E) Immunocytochemistry Differential Diagnosis Main points
Fibromatosis
The term fibromatosis was proposed by Stout for a group of related conditions having in common the following features: There are three variants of fibromatosis, apparently restricted to childhoods that present distinct clinicopathological picture: fibromatosis colli, infantile digital fibromatosis and infantile myofibromatosis (for details see Soft tissue Chapter)
Nodular fasceiitis
Clinical features Fig 29 – Nodular fasciitis- Myxoid spindle cell lesion Immunocytochemistry Genetic studies Differential Diagnosis Main points