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TERMINOLOGIA i kategorie wyników bada? wymazów z szyjki
- Historyczna perspektywa: Kryteria oceny i terminologia stosowane w interpretacji rozmazów cytologicznych i formu?owaniu wyników s? ró?ne w ró?nych krajach co stwarza trudno?ci w porozumiewaniu si? patologów, cytotechników i klinicystów oraz utrudnia epidemiologom efektywne porównanie ró?nych programów cytologicznych. Ró?norodno?c terminologiczna utrudnia merytoryczn? dyskusj? mi?dzy laboratoriami a tak?e post?powanie z pacjentk? i wdra?anie optymalnych metod opieki.
- W 1988 roku the National Cancer Institute w Stanach Zjednoczonych opracowa? System Bethesda (TBS) czyli system formu?owania wyników bada? cytologicznych szyjki macicy. W 1990 roku program Leonardo da Vinci sponsorowa? przygotowanie porównania terminologii stosowanych w tym zakresie w krajach UE z systemem Bethesda (terminologia ekwiwalentna).
- Partnerzy zaanga?owani w przygotowanie strony internetowej Eurocytology wybrali terminologi? zaproponowan? przez system Bethesda ze wzgl?du na jego szerokie rozpowszechnienie w ?wiecie. Tam gdzie to potrzebne pozostawiono linki do terminologii ekwiwalentnej.
The main categories of the Bethesda reporting system (2001) are shown below:
SPECIMEN TYPE | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Indicate whether conventional smear, endocervical brush specimen or liquid based cytology (LBC) specimen |
Indicate whether conventional smear, endocervical brush specimen or liquid based cytology (LBC) specimen |
SPECIMEN ADEQUACY | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Satisfactory for evaluation (describe presence or absence of endocervical/transformation zone component and other quality indicators e.g. partially obscuring blood etc) |
|
Specimen rejected/not processed (specify reason) |
Unsatisfactory for evaluation (specify reason) |
Specimen process and examined but unsatisfactory for evaluation of epithelial abnormality because of (specify reason) |
|
GENERAL CATEGORISATION (optional) | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Negative for intraepithelial lesion |
|
Other: see Interpretation/Results |
|
Epithelial Cell Abnormality (specify Squamous or Glandular as appropriate) |
|
INTERPRETATION / RESULTS | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Negative for intraepithelial lesion or malignancy |
Negative |
|
Within normal limits |
|
Benign cellular changes |
ORGANISMS DETECTED | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Trichomonas vaginalis |
Trichomonas vaginalis |
Fungal organisms morphologically consistent with Candida spp |
Candida spp |
Shift in flora suggestive of bacterial vaginosis |
Coccobacilli |
Bacteria morphologically consistent with Actinomyces spp |
Actinomyces spp |
Cellular changes consistent with herpes simplex virus infection |
Cellular changes indicate Herpes simplex virus infection |
OTHER NON NEOPLASTIC FINDINGS (optional; list not inclusive) | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Reactive cellular changes associated with inflammation /repair |
Reactive cellular changes associated with inflammation /repair |
Radiation |
Radiation |
Intrauterine contraceptive device |
Intrauterine contraceptive device |
Glandular cell status post hysterectomy |
Endometrial cells in a post menopausal woman |
Endometrial cells (in a woman >40year if age) |
Glandular cell inconsistent with stated age and/ clinical status of woman |
SQUAMOUS EPITHELIAL CELL ABNORMALITIES | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Atypical squamous cells
|
Borderline nuclear changes |
Low grade Squamous intraepithelial lesions (LSIL) encompassing: HPV/mild dysplasia/CIN1 |
|
High grade Squamous intraepithelial lesion (HSIL) encompassing: moderate and severe dysplasia, CIS, CIN2 and CIN3 |
|
With features suspicious for invasion |
|
Squamous cell carcinoma |
Invasive Squamous cell carcinoma |
GLANDULAR EPITHELIAL ABNORMALITIES | |
---|---|
2001 Bethesda System | Equivalent Terminology |
Atypical
|
|
|
|
Endocervical adenocarcinoma in situ |
|
Adenocarcinoma
|
Adenocarcinoma
|
IARC Handbooks of Cancer Prevention
Volume 10 Cervix Cancer Screening
Chapter 2: pp 59-67 historical revue of terminology used to describe cervical smears
Chapter 2: pp 69-74 comparison of conventional cytology with liquid based cytology