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Az invazív endocervicalis adenocarcinoma citológiai diagnózisa

Adenocarcinomain situ.
The characteristic feature of AIS is replacement of normal columnar epithelium of the endocervical canal by neoplasic cells with hyperchromatic nuclei which is clearly shown in this section. The structure of the glands is in tact.
Endocervical adenocarcinoma (well differentiated)
Endocervical adenocarcinomas are composed of branching and budding glands lined by neoplastic cells which in the well diffrerentiated carcinomas resemble the glandular cells lining the endocervical canal. The tumour is invading the stroma and there is loss of the normal gland architecture.
Endocervical adenocarcinoma (well differentiated).
Endocervical adenocarcinomas are composed of branching and budding glands lined by neoplastic cells which in the well diffrerentiated carcinomas resemble the glandular cells lining the endocervical canal. There is marked nuclear hyperchromasia, cellular crowding, and pseudostratification.
A kevéssé differenciált endocervikális adenocarcinoma inkább szolid fészkekben növekszik, a mirigy formáló készség szegényes. Egyesével a sejtek alig hasonlítanak az ép endocervixre, pleiomorph a kép és sok a mitozis.