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Granulomatous processes

Sarcoidosis and tuberculosis and other infective diseases may cause granulomatous lesions to the spleen. Hodgkin and non Hodgkin lymphoma and chemotherapy may be followed by granulomatous lesions which may cause equivocal clinical features.

Epithelioid cells (left) and granulomatous structure in a hematic background in a splenomegaly developed in a NHL patient in remission.