Lymphomas
Lymphomas Hodgkin (HL) and non Hodgkin lymphomas (NHL) may involve the spleen; HL and large cell NHL may determine nodular lesions as well as primary splenic NHL, which is generally a B- large cell NHL and presents with nodular lesions. Small cell NHL may present as diffuse or miliaric. Non invasive diagnostic procedures have drastically […]
Hodgkin lymphoma
Hodgkin lymphoma Spleen if frequently involved in advanced stages of HL giving a nodular presentation. Cytological criteria are almost the same of lymph nodes, whereas, in case of relapse, atypical mono and binucleated cells may be sufficient for the diagnosis.
Classification of splenomegalies
Disordes associated with splenomegaly INFECTIONS Non specific splenitis Mononucleosis Tuberculosis Brucellosis Malaria Histoplasmosis Leishmaniosi Echinococcosis CONGESTIVE STATES Cirrhosis Portal or splenic thrombosis Cardiac failure AUTOIMMUNE DISEASES Rheumatoid arthritis Systemic lupus erythematosus STORAGE DISEASES Gaucher disease Niemann-Pick disease Mucopolysaccaridoses LYMPHOHEMATOGENOUS DISORDERS Hodgkins lymphoma Non-Hodgkin lymphomas Histiocytoses Multiple myeloma Myeloproliferative syndromes (CML, polycytemia vera, myelofibrosis, myeloid metaplasia) […]
Spleen
General Nodular or diffuse splemomegalies may be determined by several causes; in most cases, clinical and serological data are diagnostic but there are still rare conditions or equivocal clinical presentations in which a direct evaluation may be useful. FNC of the spleen was first used for the diagnosis of leishmaniasis and was then extensively used […]