Normal cells
Normal cells Fine needle aspiration of normal pancreas yield a combination of benign acinar and ductal epithelial cells. Benign acinar epithelium cytologic features Single cells or acini Eccentrically placed, round nuclei Evenly distributed, finely granular chromatin Incospicuous nucleoli Abundant granular cytoplasm Indistinct cell borders Benign ductal epithelium cytologic features Flat, cohesive honeycomb sheets […]
Pancreatic cysts
Pancreatic cysts The evaluation of pancreatic cysts requires a multidisciplinary approach. No single diagnostic test provides 100% sensitivity and specificity. The absence of cyst lining cells implies a pseudocyst in the appropriate clinical setting, but this is a diagnosis of exclusion. In the case of cysts the fluid is separately submitted for carcinoembryonic antigen (CEA), amylase, […]
Pancreatitis
Acute pancreatitis Acute pancreatitis results from the enzymatic autodestruction of the parenchyma and the accompanying acute inflammatory response. It is most commonly associated with biliary tract disease or alcoholism. The diagnosis rests on clinical findings and laboratory evidence, and the radiologic appearance is usually not suggestive of a mass lesion. For this reason, it is […]
Solid tumors
Solid tumors Ductal adenocarcinoma Acinar cell carcinoma Solid-pseudopapillary tumor Endocrine tumors Metastatic tumors
Cystic tumors
Cystic tumors Pancreatic cystic tumors account for about 5% of pancreatic neoplasms. They also include cystic dilatations of intraductal neoplasms, cystic degenerations of solid neoplasms (solid-pseudopapillary tumor), and solid neoplasms with focal cystic change (ductal adenocarcinoma with cystic degeneration, cystic acinar cell carcinoma, cystic pancreatic endocrine tumor). Serous cystadenoma It usually occurs in elderly women, […]
Pancreas
On completion of this section the cytotechnologist should Know: the anatomy and histology of the pancreas indications of fine needle aspiration slide preparation methods indications of biliary brushing the reporting terminology cytologic features of benign acinar and ductal epithelial cells cytologic features of acute and chronic pancreatitis cytologic features of pancreatic pseudocysts cytologic features of […]