The designation of an aspirate as inadequate is sometimes subjective. The experience of the aspirator and/or the interpreter plays a decisive role. Adequacy is based on the presence of sufficient numbers of epithelial cells to provide a reliable assessment.
C1 ideal rates must be lower than 10%.
In case the lab exceeds 20% FNAs tecnicque has to be revised.
Different reasons may lead to label a smear as inadequate:
- Errors in sampling
- Bad spreading
- Poor fixation (expired fixatives, not immediate fixation)
- Inadequate drying
- Bad staining (under/over)
- Poor cellularity