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Cause of injury

Inflammatory changes in the cervix occur as a result of physical or chemical damage to the cervical mucosa. Inflammatory changes also occurs as result of cervical infection with a variety of microorganisms which may kill the cells directly or indirectly through toxins and enzymes.

Physical or chemical injury

Infectious organisms

Effects of injury

Injury to the cervical epithelium results in an inflammatory response which is charcterised by:

  1. hyperaemia of the papillary vessels
  2. exudation of fluid into the surrounding tissue
  3. migration of polymorphs to the site of infection or injury

These changes are non specific and occur regardless of the cause of the injury or infection and can be recognised in histological sections of non specific cervicitis.