Метаплазия

??????????? ?????????? ???????, ??????????? ???????? ???? ????????? ?????????????????? ??? ???????? ???????????????? ? ?????? ?????????????????? ???. ???, ??? ???????, ????????????????? ???????, ??????? ?????????? ? ????? ?? ??????????? ??????????? ??? ?? ???????????? ???????. ? ???????? ???????? ?????????? ? ??? ?????????? ??????? ???????? ? ??????? ?????????? ???????????? ?????????, ?????????? ??????? ????? ?????, ??????? ? ???? ??????? ???????? ? ????, ??? ??????? ?????????? ???????? ???????????? ????? ???????? ??????????? ?????? ????? ?????????. ??????????? ??????? ?????????? ?? ????? ????????????.
??? ??????? ??? ?????????, ?????? ??????????? ???????? “??????? ????? ?????” ??-?? ??? ???????? ???? ? ???? ???????? ??????, ??????????? ???????????? ???.            

      

???????? ??? ??????????????? ?????:

  • ???? 1: ??????????? ????????? ?????? - ????????? ?????? ? ???????????????? ???????? ???????? ????????.
  • ???? 2: ???????? ??????????????? ?????????? - ????????? ?????? ????????????? ? ???????????? ????????????? ?????? ?? ???????? ????????????? ??????. ?? ??????????? ????? ????? ??????? ???? ????????? ?????????????? ??????.
  • ???? 3: ?????? ??????????????? ?????????? - ???????? ?????? ???????????????? ? ?????? ?????? ???????? ???????? ? ????? ?????????? ?? ????????????? ???????? ????????. ??? ????????????????? ????????? ????? ??????????????? ???????????????? ??????, ??? ???????????? ????????????? ???????? ???????? ?? ??????????????? ??????????.

 

??????? 2.5. ?????????? ???????????????? ?????? ??? ??????????????? ???????????

(a) ???????? ??????????????? ?????????? ? ?????????? ???????????????? ????????
(b) ?????? ??????????????? ?????????? (????????????? ??????) ? ?????????

 

  • ? ???????? ?? ???????? ?????????? ???????????????? ????????  ??????? ?? ?????????????? ??????, ???????????????? ?? ???????? ??????? ??????. ????? ?? ????? ???????? ???????? ??????????????-?????????? ?????????.
  • ?? ????? ???????? ?????????? ? ?????? ???????????? ? ????? ?? ???????????? ????????? ????? ????? ????????????? ? ??????. ???????????????? ???????? ?????????????? ?? ??????????? (??????????? ??????), ??? ?? ???????????? ??????????? ?????? ????? ?????????, ??? ???? ?????? ??? ???????????????? ????????? ??????????????? ????????.
  • ??????? ?????????? ???????? ????????????: ?? ???????? ??????? ? ???????? ? ?? ???????? ???????????????? ??????, ??????? ?????????? ?????????. ? ????? ?????? ???? «??????????» ???????????????? ???????? ????? ???? ??????? ???????.

Figure 2.6 ???????? ??????????????? ??????????

??????????????-?????????? ??????? ?? ???????? ??????????
??????? ????????????????? ???????? ? ?????? ???????? ?????????? ? ?????? ????????????
?????????? ????????????????? ???????? ? ???? ?????????????
???????? ??????????????-??????????? ???????? ? ?????????????

 

???????? ???????:
1: ???????? ??????? ????????
2: ?????????????? ???????? ????????????
3: ??????????????-?????????? ??????? (???)
4: ??????? ????????????????? ????????
5: ?????????? ? ???? ?????????????

 

??????????? ?????????? ??????????????? ?????????? ? ????? ?????

? ????? ????? ??????? ????????, ??????? ??????????? ??????????????? ??????????? ???????? ????? ????????????? (??). ?????????????? ???????????? ????????, ??? ?????????, ??????????? ??? ?????????? ???, ?????? ?????, ????????? ? ???????? ??????? ?????????????????? ???????? ??, ??? ??????????? ???????????, ???? ?? ??? ?????? ???? ????? ?????.

 

Learning points from Chapter 2

  1. The cervix has four anatomically distinct regions: ectocervix, squamocolumnar junction (SCJ), endocervical canal and endocervix.
  2. The SCJ undergoes eversion after puberty and pregnancy and recedes into the endocervical canal at the menopause.
  3. Immature metaplasia develops as a transformation zone between the SCJ and the ectocervix from basally situated reserve cells.
  4. High-grade precancerous lesions primarily arise in the transformation zone.
  5. The endocervix is protected by a mucus plug in the endocervical canal of variable composition during reproductive cycles of life and pregnancy.

 

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