{"id":5980,"date":"2023-03-17T08:42:45","date_gmt":"2023-03-17T08:42:45","guid":{"rendered":"https:\/\/www.eurocytology.eu\/course\/carcinoma-insular\/"},"modified":"2023-04-26T09:24:31","modified_gmt":"2023-04-26T09:24:31","slug":"carcinoma-insular","status":"publish","type":"course","link":"https:\/\/www.eurocytology.eu\/es\/course\/citologia-de-tiroides\/tumores-malignos\/carcinoma-insular\/","title":{"rendered":"Carcinoma insular"},"content":{"rendered":"<div data-object_id=\"5980\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_guest cbxwpbkmarkwrap_user_cat cbxwpbkmarkwrap-course \"><a  data-redirect-url=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5980\/\"  data-display-label=\"1\" data-show-count=\"1\" data-bookmark-label=\"Bookmark\"  data-bookmarked-label=\"Bookmarked\"  data-loggedin=\"0\" data-type=\"course\" data-object_id=\"5980\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\" >Bookmark (<i class=\"cbxwpbkmarktrig-count\">0<\/i>)<\/span><\/a> <div  data-type=\"course\" data-object_id=\"5980\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-5980\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3><form name=\"loginform\" id=\"loginform\" action=\"https:\/\/www.eurocytology.eu\/wp-login.php\" method=\"post\"><p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Nombre de usuario o correo electr\u00f3nico<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" autocomplete=\"username\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Contrase\u00f1a<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" autocomplete=\"current-password\" spellcheck=\"false\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Recu\u00e9rdame<\/label><\/p><p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Acceder\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5980\/\" \/>\n\t\t\t<\/p><\/form><p class=\"cbxwpbookmark-guest-register\">No account yet? <a href=\"https:\/\/www.eurocytology.eu\/es\/register\/?redirect_to=https%3A%2F%2Fwww.eurocytology.eu%2Fes%2Fwp-json%2Fwp%2Fv2%2Fcourse%2F5980%2F\">Register<\/a><\/p><\/div><\/div><\/div><p>Algunos carcinomas de tiroides tienen un grado intermedio de atipia entre los carcinomas bien diferenciados y los carcinomas anapl\u00e1sicos. Estos carcinomas pobremente diferenciados representan &lt; del 5% de los carcinomas de tiroides. Una forma distintiva es el carcinoma insular.<\/p>\n<h3>Caracter\u00edsticas citol\u00f3gicas diagn\u00f3sticas<\/h3>\n<ul>\n<li>Alta celularidad<\/li>\n<li>Predominio de c\u00e9lulas individuales<\/li>\n<li>Grupos y microfol\u00edculos<\/li>\n<li>Nucleos redondos monom\u00f3rficos<span align=\"justify\">&nbsp;<\/span><\/li>\n<\/ul>\n<p>En preparaciones histol\u00f3gicas, las c\u00e9lulas malignas del carcinoma insular se distribuyen en nidos (\u201cinsulae\u201d) o en cintas, rodeadas por estroma. Las preparaciones citol\u00f3gicas son altamente celulares, con numerosas c\u00e9lulas tumorales aisladas y grupos de c\u00e9lulas superpuestas. En algunos casos una poblaci\u00f3n menor de grandes c\u00e9lulas pleom\u00f3rficas puede estar tambi\u00e9n presente. El citoplasma es pobremente definido, algunas veces vacuolado. Pueden observarse hendiduras nucleares y pseudoinclusiones en algunos casos. El coloide es escaso.<\/p>\n<p align=\"justify\">Cuando se encuentran los caracter\u00edsticos cambios nucleares, estos pueden sugerir un carcinoma papilar, pero el predominio de c\u00e9lulas aisladas es m\u00e1s t\u00edpico del carcinoma insular. El pleomorfismo nuclear focal puede sugerir un carcinoma anapl\u00e1sico, pero las c\u00e9lulas en forma de huso y c\u00e9lulas gigantes son poco comunes. El carcinoma insular puede semejar el carcinoma medular, pero los microfol\u00edculos con coloide pueden ayudar en el diagn\u00f3stico y la inmunocitoqu\u00edmica puede llevarse a cabo: los carcinoma insulares son tiroglobulina positivos y calcitonina negativos.<\/p>\n<p align=\"justify\">Un diagn\u00f3stico correcto es rara vez llevado a cabo mediante el aspirado con aguja fina; este puede realizarse con certeza solo despu\u00e9s del examen histol\u00f3gico. La mayor\u00eda de muestras son diagnosticadas como neoplasias foliculares o como carcinomas metast\u00e1ticos.<\/p>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img fetchpriority=\"high\" decoding=\"async\" alt=\"\" height=\"675\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture1_11.jpg\" width=\"446\" \/><\/a><figcaption>A crowded group of epithelial cells with coarse chromatin and higher N\/C ratio (MGG) &#8211; A rather crowded group of epithelial cells with coarse chromatin and higher N\/C ratio than found in usual follicular lesions. Often discohesive such cells are found in the background (MGG).<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img decoding=\"async\" alt=\"\" height=\"675\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture2_8.jpg\" width=\"450\" \/><\/a><figcaption>The nuclei have irregular outlines and chromatin pattern (Pap) &#8211; A goup of cells reminiscent of a follicle but lacking colloid. The nuclei have irregular outlines and chromatin pattern; the N\/C ratio is high. These features and the overall cellularity suggested a follicular neoplasm with suspicious features. Histology classified it as an insular carcinoma.&nbsp;<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<div data-object_id=\"5980\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_guest cbxwpbkmarkwrap_user_cat cbxwpbkmarkwrap-course \"><a  data-redirect-url=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5980\/\"  data-display-label=\"1\" data-show-count=\"1\" data-bookmark-label=\"Bookmark\"  data-bookmarked-label=\"Bookmarked\"  data-loggedin=\"0\" data-type=\"course\" data-object_id=\"5980\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\" >Bookmark (<i class=\"cbxwpbkmarktrig-count\">0<\/i>)<\/span><\/a> <div  data-type=\"course\" data-object_id=\"5980\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-5980\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3><form name=\"loginform\" id=\"loginform\" action=\"https:\/\/www.eurocytology.eu\/wp-login.php\" method=\"post\"><p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Nombre de usuario o correo electr\u00f3nico<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" autocomplete=\"username\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Contrase\u00f1a<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" autocomplete=\"current-password\" spellcheck=\"false\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Recu\u00e9rdame<\/label><\/p><p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Acceder\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5980\/\" \/>\n\t\t\t<\/p><\/form><p class=\"cbxwpbookmark-guest-register\">No account yet? <a href=\"https:\/\/www.eurocytology.eu\/es\/register\/?redirect_to=https%3A%2F%2Fwww.eurocytology.eu%2Fes%2Fwp-json%2Fwp%2Fv2%2Fcourse%2F5980%2F\">Register<\/a><\/p><\/div><\/div><\/div><p>Algunos carcinomas de tiroides tienen un grado intermedio de atipia entre los carcinomas bien diferenciados y los carcinomas anapl\u00e1sicos. Estos carcinomas pobremente diferenciados representan &lt; del 5% de los carcinomas de tiroides. Una forma distintiva es el carcinoma insular. Caracter\u00edsticas citol\u00f3gicas diagn\u00f3sticas Alta celularidad Predominio de c\u00e9lulas individuales Grupos y microfol\u00edculos Nucleos redondos monom\u00f3rficos&nbsp; En [&hellip;]<\/p>\n","protected":false},"featured_media":0,"parent":5970,"menu_order":1,"template":"","meta":[],"tags":[],"course_area":[115],"authors":[],"class_list":["post-5980","course","type-course","status-publish","hentry","course_area-citologia-de-tiroides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Carcinoma insular - Eurocytology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.eurocytology.eu\/es\/course\/citologia-de-tiroides\/tumores-malignos\/carcinoma-insular\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Carcinoma insular - Eurocytology\" \/>\n<meta property=\"og:description\" content=\"Algunos carcinomas de tiroides tienen un grado intermedio de atipia entre los carcinomas bien diferenciados y los carcinomas anapl\u00e1sicos. Estos carcinomas pobremente diferenciados representan &lt; del 5% de los carcinomas de tiroides. Una forma distintiva es el carcinoma insular. 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