{"id":5973,"date":"2023-03-17T08:42:44","date_gmt":"2023-03-17T08:42:44","guid":{"rendered":"https:\/\/www.eurocytology.eu\/course\/evaluacion-de-la-muestra\/"},"modified":"2023-04-26T09:24:28","modified_gmt":"2023-04-26T09:24:28","slug":"evaluacion-de-la-muestra","status":"publish","type":"course","link":"https:\/\/www.eurocytology.eu\/es\/course\/citologia-de-tiroides\/evaluacion-de-la-muestra\/","title":{"rendered":"Evaluaci\u00f3n de la muestra"},"content":{"rendered":"<div data-object_id=\"5973\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_guest cbxwpbkmarkwrap_user_cat cbxwpbkmarkwrap-course \"><a  data-redirect-url=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5973\/\"  data-display-label=\"1\" data-show-count=\"1\" data-bookmark-label=\"Bookmark\"  data-bookmarked-label=\"Bookmarked\"  data-loggedin=\"0\" data-type=\"course\" data-object_id=\"5973\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\" >Bookmark (<i class=\"cbxwpbkmarktrig-count\">0<\/i>)<\/span><\/a> <div  data-type=\"course\" data-object_id=\"5973\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-5973\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3><form name=\"loginform\" id=\"loginform\" action=\"https:\/\/www.eurocytology.eu\/wp-login.php\" method=\"post\"><p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Nombre de usuario o correo electr\u00f3nico<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" autocomplete=\"username\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Contrase\u00f1a<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" autocomplete=\"current-password\" spellcheck=\"false\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Recu\u00e9rdame<\/label><\/p><p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Acceder\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5973\/\" \/>\n\t\t\t<\/p><\/form><p class=\"cbxwpbookmark-guest-register\">No account yet? <a href=\"https:\/\/www.eurocytology.eu\/es\/register\/?redirect_to=https%3A%2F%2Fwww.eurocytology.eu%2Fes%2Fwp-json%2Fwp%2Fv2%2Fcourse%2F5973%2F\">Register<\/a><\/p><\/div><\/div><\/div><p>Varias caracter\u00edsticas se deben considerar en la evaluaci\u00f3n de una muestra:<\/p>\n<ul>\n<li>El tipo de c\u00e9lula (tal como c\u00e9lula tiroidea, macr\u00f3fagos, linfocitos)<\/li>\n<\/ul>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img fetchpriority=\"high\" decoding=\"async\" alt=\"\" height=\"503\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture4_1.jpg\" width=\"671\" \/><\/a><figcaption><strong>Thyrocytes and macrophages.&nbsp;<\/strong>Fluid colloid in the background, bland thyrocytes and pigmented macrophages.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img decoding=\"async\" alt=\"\" height=\"325\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture5_0.jpg\" width=\"433\" \/><\/a><figcaption><strong>Lymphocytes and thyrocytes.&nbsp;<\/strong>A group of bland thyroid cells showing a follicular arrangement, surrounded by smaller lymphoid cells with little amount of identifiable cytoplasm. Such lymphoid cells are also inside the follicular group, suggesting chronic inflammation.<\/figcaption><\/figure>\n<ul>\n<li>La cantidad y tipo de coloide (escaso-abundante, fluido-denso)<\/li>\n<\/ul>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img decoding=\"async\" alt=\"\" height=\"503\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture8.jpg\" width=\"670\" \/><\/a><figcaption><strong>Colloid:<\/strong> Fluid but relatively thick colloid with the typical cracks which are produced with air drying. These are artefacts which are useful in recognising colloid.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"503\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture3_0.jpg\" width=\"670\" \/><\/a><figcaption><strong>Colloid:&nbsp;<\/strong>A clump of thicker colloid surrounded by few bare nuclei. In the appropriate context this type of colloid may be associated with papillary carcinoma.<\/figcaption><\/figure>\n<ul>\n<li>La celularidad (escasa, moderada o marcada)<\/li>\n<\/ul>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"1200\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/picture10_3.jpg\" width=\"1600\" \/><\/a><figcaption><strong>Highly cellular smear showing a microbiopsy.<\/strong> A microbiopsy, as may be&nbsp; obtained with larger needles, in which 3D follicles are separated by collagenous septa; the margins of the follicles are regular. This pattern is usually seen in FNAs from nodular goitres. Please note that in air dried samples stained with MGG the centre of these microbiopsies will be too thick to assess.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"581\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture1_2.jpg\" width=\"775\" \/><\/a><figcaption>Less cellular but diagnostic smear showing groups of bland thyroid cells in a microfollicular arrangement, bare nuclei of thyroid cells and fluid colloid in the background. A few macrophages are also present. This pattern is associated with benign disease.<\/figcaption><\/figure>\n<ul>\n<li>La arquitectura (monocapas, grupos api\u00f1ados, s\u00e1banas, macro\/microfol\u00edculos, grupos papilares, c\u00e9lulas aisladas)<\/li>\n<\/ul>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"950\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture2_2.jpg\" width=\"1267\" \/><\/a><figcaption><strong>Sheets of bland thyroid cells.<\/strong>&nbsp;A monolayered sheet of bland thyroid cells. Note the regular distribution of the nuclei and cytoplasm and very fine chromatin with small nucleoli.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"503\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture21.jpg\" width=\"670\" \/><\/a><figcaption><strong>Sheets of bland thyroid cells.<\/strong>&nbsp;Another example of a a monolayered sheet of bland thyroid cells. Because of the size of this sheet some areas may appear more crowded but are actually simply folded. It is good practice to focus on these areas to check the regular distribution of cells along the same plane. Such large sheets are usually lining larger follicles or cysts in&nbsp; benign disease.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"503\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture1_3.jpg\" width=\"670\" \/><\/a><figcaption><strong>Thyroid cells in a microfollicular arrangement.<\/strong>&nbsp;Several groups of thyroid cells in a microfollicular arrangement. In follicular lesions this may be the only type of cell present.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"900\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture10.jpg\" width=\"1200\" \/><\/a><figcaption><strong>A papillary cluster<\/strong> with the epithelial cells lying perpendicular to the stromal axis. The typical nuclear features of papillary carcinoma need to be present however for a diagnosis of papillary carcinoma.<strong>.<\/strong><\/figcaption><\/figure>\n<ul>\n<li>La presencia de n\u00facleos desnudos<\/li>\n<\/ul>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"950\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture3_2.jpg\" width=\"1267\" \/><\/a><figcaption>Many bare nuclei are seen dispersed together with bland thyroid cells in a follicular arrangement. Note that the chromatin pattern is the same, confirming that these nuclei have been stripped of their fragile cytoplasm during the smearing procedure. Lymphocytes are smaller, have a more granular chromatin, folded&nbsp; nuclear membrane and scanty but clearly identifiable, dense cytoplasm.<\/figcaption><\/figure>\n<ul>\n<li>Caracter\u00edsticas citol\u00f3gicas (citoplasma, n\u00facleo)<\/li>\n<\/ul>\n<p>En lesiones neopl\u00e1sicas las muestras son con frecuencia altamente celulares. Las s\u00e1banas planas son comunes en el bocio y los adenomas macrofoliculares, pero pueden tambi\u00e9n estar presentes en carcinomas. Los macrofol\u00edculos est\u00e1n usualmente asociados con el bocio multinodular y los adenomas macrofoliculares. Un predominio de microfol\u00edculos puede ser sugestivo de neoplasia folicular. Los grupos papilares, con c\u00e9lulas recubriendo un tallo fibrovascular, son caracter\u00edsticos del carcinoma papilar. Los frotis con una alta proporci\u00f3n de coloide a c\u00e9lulas foliculares usualmente es indicativo de un n\u00f3dulo benigno.<\/p>\n<h3>Caracter\u00edsticas citol\u00f3gicas:<\/h3>\n<ul>\n<li class=\"rteindent1\">citoplasma (cantidad, tinci\u00f3n)<\/li>\n<li class=\"rteindent1\">patr\u00f3n de cromatina<\/li>\n<li class=\"rteindent1\">membrana nuclear (suave o irregular)<\/li>\n<li class=\"rteindent1\">hendiduras nucleares y pseudoinclusiones<\/li>\n<\/ul>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"507\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture18.jpg\" width=\"675\" \/><\/a><figcaption><strong>Abundant cytoplasm containing granules.<\/strong> A group of large non cohesive cells with abundant dense, cytoplasm containing granules. The nuclei are single or multiple and pleomorphic. The differential includes H\u00fcrthle cells (oncocytic change), \u201csquamoid&#8221; cells in papillary carcinoma or goitre and atypical cells in anaplastic carcinoma.<\/figcaption><\/figure>\n<figure><a data-toggle=\"modal\" href=\"#modal-container-2\"><img loading=\"lazy\" decoding=\"async\" alt=\"\" height=\"226\" src=\"http:\/\/lnx.eurocytology.eu\/sites\/default\/files\/styles\/max\/public\/images\/Picture26.jpg\" width=\"336\" \/><\/a><figcaption><strong>Nuclear pseudoinclusions and groovings.<\/strong>&nbsp;A cluster of large cells with abundant, polygonal and dense cytoplasm; the nuclei in this case show all the features of papillary carcinoma (nuclear pseudoinclusions, grooving).<\/figcaption><\/figure>\n","protected":false},"excerpt":{"rendered":"<div data-object_id=\"5973\" class=\"cbxwpbkmarkwrap cbxwpbkmarkwrap_guest cbxwpbkmarkwrap_user_cat cbxwpbkmarkwrap-course \"><a  data-redirect-url=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5973\/\"  data-display-label=\"1\" data-show-count=\"1\" data-bookmark-label=\"Bookmark\"  data-bookmarked-label=\"Bookmarked\"  data-loggedin=\"0\" data-type=\"course\" data-object_id=\"5973\" class=\"cbxwpbkmarktrig  cbxwpbkmarktrig-button-addto\" title=\"Bookmark This\" href=\"#\"><span class=\"cbxwpbkmarktrig-label\" >Bookmark (<i class=\"cbxwpbkmarktrig-count\">0<\/i>)<\/span><\/a> <div  data-type=\"course\" data-object_id=\"5973\" class=\"cbxwpbkmarkguestwrap\" id=\"cbxwpbkmarkguestwrap-5973\"><div class=\"cbxwpbkmarkguest-message\"><a href=\"#\" class=\"cbxwpbkmarkguesttrig_close\"><\/a><h3 class=\"cbxwpbookmark-title cbxwpbookmark-title-login\">Please login to bookmark<\/h3><form name=\"loginform\" id=\"loginform\" action=\"https:\/\/www.eurocytology.eu\/wp-login.php\" method=\"post\"><p class=\"login-username\">\n\t\t\t\t<label for=\"user_login\">Nombre de usuario o correo electr\u00f3nico<\/label>\n\t\t\t\t<input type=\"text\" name=\"log\" id=\"user_login\" autocomplete=\"username\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-password\">\n\t\t\t\t<label for=\"user_pass\">Contrase\u00f1a<\/label>\n\t\t\t\t<input type=\"password\" name=\"pwd\" id=\"user_pass\" autocomplete=\"current-password\" spellcheck=\"false\" class=\"input\" value=\"\" size=\"20\" \/>\n\t\t\t<\/p><p class=\"login-remember\"><label><input name=\"rememberme\" type=\"checkbox\" id=\"rememberme\" value=\"forever\" \/> Recu\u00e9rdame<\/label><\/p><p class=\"login-submit\">\n\t\t\t\t<input type=\"submit\" name=\"wp-submit\" id=\"wp-submit\" class=\"button button-primary\" value=\"Acceder\" \/>\n\t\t\t\t<input type=\"hidden\" name=\"redirect_to\" value=\"https:\/\/www.eurocytology.eu\/es\/wp-json\/wp\/v2\/course\/5973\/\" \/>\n\t\t\t<\/p><\/form><p class=\"cbxwpbookmark-guest-register\">No account yet? <a href=\"https:\/\/www.eurocytology.eu\/es\/register\/?redirect_to=https%3A%2F%2Fwww.eurocytology.eu%2Fes%2Fwp-json%2Fwp%2Fv2%2Fcourse%2F5973%2F\">Register<\/a><\/p><\/div><\/div><\/div><p>Varias caracter\u00edsticas se deben considerar en la evaluaci\u00f3n de una muestra: El tipo de c\u00e9lula (tal como c\u00e9lula tiroidea, macr\u00f3fagos, linfocitos) Thyrocytes and macrophages.&nbsp;Fluid colloid in the background, bland thyrocytes and pigmented macrophages. Lymphocytes and thyrocytes.&nbsp;A group of bland thyroid cells showing a follicular arrangement, surrounded by smaller lymphoid cells with little amount of identifiable [&hellip;]<\/p>\n","protected":false},"featured_media":0,"parent":5951,"menu_order":0,"template":"","meta":[],"tags":[],"course_area":[115],"authors":[],"class_list":["post-5973","course","type-course","status-publish","hentry","course_area-citologia-de-tiroides"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.6 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Evaluaci\u00f3n de la muestra - Eurocytology<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.eurocytology.eu\/es\/course\/citologia-de-tiroides\/evaluacion-de-la-muestra\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Evaluaci\u00f3n de la muestra - Eurocytology\" \/>\n<meta property=\"og:description\" content=\"Varias caracter\u00edsticas se deben considerar en la evaluaci\u00f3n de una muestra: El tipo de c\u00e9lula (tal como c\u00e9lula tiroidea, macr\u00f3fagos, linfocitos) Thyrocytes and macrophages.&nbsp;Fluid colloid in the background, bland thyrocytes and pigmented macrophages. 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