Metastatic tumours

The lungs are a very common site for metastasis. Metastases are diagnosed in sputum in up to 70% of cases.

  • Squamous carcinomas from aerodigestive tract
  • Breast carcinoma
  • Renal cell carcinoma
  • Adenocarcinomas from digestive tract
  • Bladder carcinoma
  • Male and female genital tract malignancies
  • Thyroid carcinoma
  • Melanoma
  • Hematopoietic malignancies
  • Sarcoma

Confirming metastatic disease is a major indication for transthoracic FNA.

Primary sites for some metastatic tumors can be inferred based on their characteristic cytologic features, but the clinical history is particularly important. Tissue-specific markers can be assessed on cell block preparations; immunocytochemistry is often helpful in distinguishing primary from metastatic disease and in identifying the origin of metastasis.

Breast
Colon
FNA meta renis? carc

Signet ring carcinoma:

Signet ring carcinoma
Signet ring carcinoma

Renal clear cell carcinoma:

Renal clear cell carcinoma
Renal clear cell carcinoma

Oncocytic thyroid carcinoma:

Oncocytic thyroid carcinoma
Oncocytic thyroid carcinoma
Oncocytic thyroid carcinoma

Metastatic epidermoid carcinoma:

Metastatic epidermoid carcinoma
Metastatic epidermoid carcinoma

Metastatic breast carcinoma:

Metastatic breast carcinoma
Metastatic breast carcinoma

Varoius:

Metastatic sarcoma
Soft tissue sarcoma
ER positive
Bronchial brush breast

 

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