Classification of splenomegalies

Disordes associated with splenomegaly

INFECTIONS

  • Non specific splenitis
  • Mononucleosis
  • Tuberculosis
  • Brucellosis
  • Malaria
  • Histoplasmosis
  • Leishmaniosi
  • Echinococcosis

CONGESTIVE STATES

  • Cirrhosis
  • Portal or splenic thrombosis
  • Cardiac failure

AUTOIMMUNE DISEASES

  • Rheumatoid arthritis
  • Systemic lupus erythematosus

STORAGE DISEASES

  • Gaucher disease
  • Niemann-Pick disease
  • Mucopolysaccaridoses

LYMPHOHEMATOGENOUS DISORDERS

  • Hodgkin’s lymphoma
  • Non-Hodgkin lymphomas
  • Histiocytoses
  • Multiple myeloma
  • Myeloproliferative syndromes (CML, polycytemia vera, myelofibrosis, myeloid metaplasia)
  • Leukemias
  • Hemolitic anemias

MISCELLANEOUS

  • Amyloidosis
  • Primary neoplasms and cysts
  • Metastases
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