It is a large B-cell lymphoma which presents as a pleural, pericardial or peritoneal effusion. There is no associated mass lesion or lymphadenopaty. Most cases arise in the setting of HIV infection. The prognosis is poor.
Cytologic diagnostic features
Dispersed large cells
Round or irregular nuclei, prominent nucleoli
Abundant basophilic cytoplasm (Romanowsky stain)
Flow Cytometry on a fresh sample confirms the morphological findings
WE WOULD WELCOME YOUR FEEDBACK!
Thank you for visiting Eurocytology. Would you like to participate in our brief SURVEY to let us know how we can improve your experience? Click here to open the survey in a new window, then go to it at the conclusion of your visit. Thank you! - Eurocytology Team