The designation of an aspirate as “inadequate” is sometimes subjective. The experience of the aspirator and/or the interpreter plays a decisive role. Adequacy is based on the presence of sufficient numbers of epithelial cells to provide a reliable assessment.
C1 ideal rates must be lower than 10%.
In case the lab exceeds 20% FNA’s tecnicque has to be revised.
Different reasons may lead to label a smear as inadequate:
Errors in sampling
Poor fixation (expired fixatives, not immediate fixation)
Bad staining (under/over)
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