Inflammatory pseudotumor

Clinical features

  • Possible symptoms: fever, abdominal pain, vomiting, diarrhoea and jaundice
  • Hypergammaglobulinemia

 

Fig 75 - Inflammatory pseudotumor – Sheet of fibroblasts/ myofibroblasts mixed with inflammatory cells (H&E)

 

  • Inflammatory cells (plasma cells, eosinophil’s and neutrophils)
  • Macrophages
  • Fibroblasts/myofibroblasts
  • Reactive atypical hepatocytes or atypical bile duct epithelial cells

 

Immunocytochemistry

Non-contributory

 

Modern diagnostic techniques

  • Non contributory

 

Differential diagnosis

  • Mesenchymal hamartoma
    • Absence of inflammatory cells
    • Differential diagnosis may be difficult

 

Main points

  • Excision is advised
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