Αντιδραστικές κυτταρολογικές αλλοιώσεις

?? ?????????? ??? ??????  ??? ?????????

????? ??? ?????????? ????????? ???? ?? ?????????? ??? ?????????? ????????? ?????????????? ??? ???????????? ??? ?????????? ?????????? ???? ????. ??? ?????? ??? ?????? ??????? ???????? ??????????? ???????? ??? ??????????? ???????? ??? ????????? ???????????? ?????????? ??? ????????????? ??? ???????? ???????.

??? ?????????? ?????? ?? ????????? ?? ?????????? ?????????? ??? ?????????? ???? ??????????? ??? ????????? ??? ??????????? ??? ??????. ??????? ???????? ????????? ???? ?? ??????? ? ???????? ??? ???? ??? ???????, ?????????? ?????? ???? ???????????? ????, ???????????? ???????? ??????? ???? ?????, ??? ???????????? ??? ???????????????? ???? ??????? ??? ???????? ? ??????.

????? ?? ?????????? ???? ???? ????? ??-??????? ??? ?????????? ??????????? ??? ?????? ??? ??????.

 

?????????????? ?????????? ??? ??????

??? ?? ????????? ????????? ???? ?????? ??? ???? «?????????»  ??????? ?????? ?? ??????? ????? ???? ?? ??????????? ??????? ???? ?? ?????, ??? ??? ?? ??????? ??? ?????????? ???? ?????????? ??? ???????????? ?? ?? ????? ?????????.

 

???????????? ??????????

?? ????????????? ??? ???????? ?????????? ???????????? ?????????? ?? ????????? ??????? ??? ???? ???????????? ?????, ?? ????????????? ????? ????????? ??? ???????????? ????????? ?? ????????? ? ????? ??????? ??? ????????????????, ??????? ?? ?????????? ?? ????????? ?? ??????????? ?? ??? ????????????? ????? ??????. ???????????? ???? ????? ??????? ???? ???????????? ????????? ?? ?????????? ??????????? (????????????? ????????). ??????????? ??????????????? ????? ??????? ?? ???????????? ??? ?????????.

?? ??????? ??? ???????????? ???????? ?????? ???????????? ???????????? ? ????????????? (???? ??? ?? ?????????? ???? ?????? ??? ?????????????? ??? ????? ??? ??? ????????? ????????) ????????? ?????? ?? ???????. ? ??????? ???? ??? ???? ???????? ???????? ?? ???????????? ??????????. ?????? ????????? ?????????? (???????? ????????) ??? ????????? (???????? ???????). ? ??????????? ????????? ?? ?????????? ?????? ???????? ??????? ?? ???????? ???? ?????????? ??????????????? ?? ????????????. ?????? ?? ??????????????? ????? ???? ????? ??? ???????????? ?? ?????????? ??????? ??? ????????? ??? ?? ????????? ????????? ??? ????????, ??? ?????? ?????? ?? ???????????? ??????????? ?????????? ????????.

 

????????????? ??????????

? ???????? ??? ??????????? ? ??????????? ????????? ???? ?? ?????????? ??? ?????????????? ??? ???????? ??? ??????? ????????? ??? ?????????? ????????? ????????? ??? ??? ????????/???????? ??? ????????? ???????? ??? ??????? ?????????? ??? ???????. ?????? ? «????????????» ??????? ?????????? ??? ??????? ???????????? ??????? ??? ?????? ????????????? ?? ????? ???????? ? ?????????? ????????.

????????????? ?????????? ??????????????? ???  ???????????? ???????????? ??????????? ??? ???????? ????????????? ???????? ?? ???????? ??????? ??? ????????? ??????? ? ??????????? ????????????? ???????? ???????? ?????????????.  

The high-power appearance in LBC is illustrated in Figure 9b-13 (a) below, which is reproduced from Figure 29 from Denton et al. (2008).

When these changes are extreme they may mimic neoplasia representing potential false positive reports.

 

Figure 9b-13b: Repair change at low power in a conventional smear showing prominent nucleoli and occasional mitoses
Figure 9b-13b. High-power appearance in LBC preparation (reproduced from Figure 29 in Denton et al. 2008)

 

 

 

????? ???????????? ??????????? ???? ???????

???????? ???????????

?? ????????? ???????? ????? ????????? ?????????? ?? ????????. ??? ???????? ????????? ???? ???? ???? ??? ?????? ????????, ???????? ????? ??????????????? ??? ???????? ??????? ??? ?? ?????????? ??????? ?????????? ???????????? ?????????? ???? ???????? ??????? ??? ??????????. 

?????? ???????????

???? ? ????? ???????, ???????????? ??? ??????????????? ????????????? ???? ??????????? ??????? ??? ????? ?? ???????? ???????? ?????? ??? ???????????????? ??? ?????????. ?? ???????????? ???????????? ???? ????????? ?? ??? ?????????? ???????? ??????, ?? ??????? ???????? ?? ????-?????????????? ???????, ?? ???????? ????????? ????????????? ?????????? ???? ???????????? ??? ????????????.

?????? ?????????????? ??????????? ?????????????? ??? ???????? ???????????????? ??? ????????????? ??? ?????????.  ?????? ??? ?? ?????????? ??????? ?????????? ?????? ?????????? ????? ??????? ?? ??????????????? ????? ??????????

 

??????????  ???????????

??????????  ??????????? ????? ? ????????? ??? ?????????????? ??? ??? ?????? ??? ???????? ???????? ???? ??? ?????????? ??? ?????????????? ?????????.?????? ?? ?????? ?? ??????????? ?????? ???? ????? ??? ????? ??  ????-??????????????? ???????? ???? ?? ??????? ??????? ??????????? ??? ?????, ????????? ???????? ???????? ??? ?????? ????????? ?? ?? ????????. ?? ????????? ???????? ????????? ???????, ???? ????? ??? ??? ???????, ?? ??????????? ?????? ??????????????. ????????? ????? "tingible-body” ?????? ?????????????. ?????????????? ??-??????? ???????????? ??? ????????????? ?????????? ?????? ?? ???????????? ??? ??????????? ?????????? ???????.

 

????? 9?-14. ??????????  ???????????: ???????????? ???????? ???????? ??? ?????? ????????? ????? “tingible-body“

 

??-?????? ??????????? ??? ???????????????

??-?????? ????????, ???????????????, ???????????? ??? ???????? ??????????? ??????? ?? ???????? ?????????????? ?????????, ??? ????????????? ??? ????????????? ???? ??????? «???????».

 

????? 9?-15. ???????????? ???????? ?? ??? ????????? ??-??????? ???????????? ?? ?????????? ???????????????: ????????? ???????, ????? ????????? ??? ???????????? ????????? ?????????.  ?????? ????????????? ????????.

 

 

????? 9?-16.  ????????????? ??????? ?? ??????? ??? ???????? ??????? ??? ??????? ???????????? ??????? ??? ??????????? ?? ????????????? ????????: ???????? ?????????, ????????? ??? ??????? ??? ???????????? ???????, ????? ??? ??????????? ????????? ????????? ??? ?????? ????????????.

 

Learning points from Chapter 9b

  1. Normal squamous cells, immature metaplastic cells and endocervical cells should be seen on a normal LBC or conventional cervical cytology slide.
  2. Endometrial cells, histiocytes, lymphocytes may also be seen and must be distinguished from mature and immature squamous and endocervical cells.
  3. Lactobacilli may be seen in normal cervical smears often in those showing cytolysis and bare nuclei.
  4. Candida, Trichomomas, Herpesvirus and Actinomyces may be seen in otherwise normal cervical cytology slides.
  5. Cytologists must recognise reactive and regenerative changes seen non-specific and specific infections as well as in atrophy and atrophic vaginitis.

 

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